Insulin-like growth factor 1 (IGF-1) therapy: Mitochondrial dysfunction and diseases

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Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1.

Insulin-like growth factor (IGF)-1 is an important neurotrophic hormone. Deficiency of this hormone has been reported to influence the genesis of cognitive impairment and dementia in the elderly patients. Nevertheless, there are studies indicating that cognitive function can be maintained into old age even in the absence of circulating IGF-1 and studies that link IGF-1 to an acceleration of neu...

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Insulin-like growth factor 1 (IGF-1): a growth hormone.

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

سال: 2016

ISSN: 0925-4439

DOI: 10.1016/j.bbadis.2016.03.010